- These findings raise the possibility that “mTOR inhibitors”* (like rapamycin and RAD001) may have beneficial effects on aging and aging-related conditions in humans.
- Since it would take decades to test the effect of a drug on life span in humans, the researchers at Novartis Institutes for BioMedical Research and affiliates used a proxy: the decline in immune function in seniors’ (age 65 and older) during aging, as assessed by their response to a flu vaccine.
- lthough some scientists are reportedly already self-medicating, “the toxicity of RAD001 at doses used in oncology or organ transplantation results in adverse effects such as stomatitis, diarrhea, nausea, cytopenias, hyperlipidemia, and hyperglycemia.”
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