- The delivery vehicle requires a pair of “parent” nanoparticles, which have a cylindrical shape and are composed of complementary polymer chains.
- When located in close proximity, the polymer chains undergo a structural change known as “stereocomplexation”. The two nanoparticles then fuse into one, releasing their drug cargo in the process.
- The researchers suggest that this method will improve drug delivery and reduce the unwanted side effects of having active chemicals flowing through the bloodstream. This is because of the low probability of sterocomplexation occuring in the circulation; when the two parent molecules both enter the same cell, they are more likely to run into each other and release the drug.
New "triggered-release" mechanism could improve drug delivery
1. 23. 15 by MolecularMatt