- Salk Institute scientists used specifically engineered molecular scissors to snip out mutations in embryos, leaving healthy DNA intact.They were able to recognise and cut out disease-causing mtDNA in mouse embryos, and the resulting offspring were healthy.
- Researchers also used the technique successfully on faulty human mtDNA, inserted into mouse eggs.They say the next step is to run preliminary laboratory tests on discarded human embryos.
- If proven safe and effective, they argue it would provide a simpler alternative to mitochondrial transfer therapy recently given the green light by UK authorities.
Mitochondria Editing Tried in Mice
4. 27. 15 by Alex Klokus