---
title: "Gene-Hacking Mosquitoes to Be Infertile Backfired Spectacularly"
description: "On its surface, the plan was simple: gene-hack mosquitoes to make them harmless, mix them with disease-spreading bugs in the wild, and watch the population drop off. Unfortunately, that didn’t quite pan out. The genetically-altered mosquitoes did mix with the wild population, and for a brief while the number of mosquitoes in Jacobino, […]"
date: "2019-09-16"
modified: "2019-09-16"
authors:
  - name: "Dan Robitzski"
    link: "https://futurism.com/authors/danrobitzski"
url: "https://futurism.com/the-byte/gene-hack-mosquitoes-backfiring"
categories:
  - "Cybersecurity"
  - "Future Society"
  - "Hacking"
  - "Science & Energy"
tags:
  - "CRISPR"
  - "gene-hack"
  - "mosquitoes"
  - "the digest"
---

# Gene-Hacking Mosquitoes to Be Infertile Backfired Spectacularly

![When scientists released gene-hacked mosquitoes into the wild population in Jacobino, Brazil, they thought it would quell the bugs. They had no such luck.](<https://futurism.com/wp-content/uploads/2019/09/gene-hack-mosquitoes-backfiring.jpg>)
*\<em\>Image: Victor Tangermann\</em\>*

## Best-Laid Plans

On its surface, the plan was simple: gene-hack mosquitoes so their offspring immediately die, mix them with disease-spreading bugs in the wild, and [watch the population drop off](<https://futurism.com/neoscope/gene-drive-mosquitos-crispr>). Unfortunately, that didn't quite pan out.

The genetically-altered mosquitoes did mix with the wild population, and for a brief period the number of mosquitoes in Jacobino, Brazil did plummet, [according to research](<https://www.nature.com/articles/s41598-019-49660-6>) published in *Nature Scientific Reports* last week. But 18 months later the population bounced right back up, [*New Atlas* reports](<https://newatlas.com/science/genetic-engineering-mosquito-experiment-goes-wrong/>) — and even worse, the new genetic hybrids may be even more resilient to future attempts to quell their numbers.

## Desperate Times

Mosquitoes capable of transmitting dangerous diseases like Zika, dengue, and malaria are [spreading farther than ever](<https://futurism.com/neoscope/mosquitoes-florida-deadly-brain-virus>), thanks to global climate change. To combat them, scientists have sometimes tried to [alter the bugs' genetics](<https://futurism.com/neoscope/genetically-engineered-mosquitoes-africa>) so that they couldn't reproduce.

"The claim was that genes from the release strain would not get into the general population because offspring would die," Yale researcher Jeffrey Powell, one of the researchers behind the new paper, told *New Atlas*. "That obviously was not what happened."

## Playing God

In Brazil, the wild mosquitoes mated with the gene-hacked population and created a new sort of genetic hybrid that's more robust than the wild bugs were. While the new variant isn't inherently dangerous — or at least not additionally so — the scientists behind the project say they don't fully understand how things will change for future generations.

"It is the unanticipated outcome that is concerning," Powell told *New Atlas.*

**READ MORE:** [Failed GM mosquito control experiment may have strengthened wild bugs](<https://newatlas.com/science/genetic-engineering-mosquito-experiment-goes-wrong/>) \[*New Atlas*\]

**More on mosquitoes:** *[Mosquito "Birth Control" Could Prevent Millions of Deaths](<https://futurism.com/neoscope/mosquito-birth-control-prevent-deaths>)*

## Author
Dan Robitzki is a senior reporter for Futurism, where he likes to cover AI, tech ethics, and medicine. He spends his extra time fencing and streaming games from Los Angeles, California.

### Author social links  
[Twitter](<https://x.com/danrobitzski>)