- Because obtaining live human serotonin neurons to study disease have been near impossible, almost all prior research has been done using lab animals. This research completely changes this paradigm by generating human serotonin in a petri dish.
- To produce the serotonergic neurons from fiberblasts, the team introduced four genes that typically control development. The result was neurons that were electrophysiologically active and demonstrate both the controlled release and the selective uptake of serotonin.
- Such induced serotonin neurons are extremely beneficial since they can be generated from individual patients suffering from illnesses involving the neurotransmitter. The team is also optimistic that the same technology is versatile enough that it can be used to generate other new cells and tissues, including neurons and heart cells.
Scientists Grow Human Serotonin Neurons in Petri Dish
8. 6. 15 by Alex Klokus