• The study suppressed one specific helicase and one gene in Caenorhabditis elegans and found that the roundworms' lifespan doubled compared to wild roundworms.
  • Although RNA helicase is well-studied, this is one of the first times their effects on the aging process have been documented.
  • The particular helicase, HEL-1, is found in mammals, including humans. In the study published this week in PNAS, the researchers claimed that "our work may have direct implications in mammalian aging, and the human HEL-1 homolog may work with FOXO to increase lifespan.

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