---
title: "Study Suggests That Pill Can Cut Hereditary Cancer Risk by 60 Percent"
description: "A new study shows that resistant starch has an astonishing ability to help prevent a range of hereditary cancers, cutting risk by 60 percent."
date: "2022-07-28"
modified: "2022-07-28"
authors:
  - name: "Maggie Harrison Dupré"
    job_title: "Senior Staff Writer"
    link: "https://futurism.com/authors/mharrison"
url: "https://futurism.com/neoscope/study-pill-hereditary-cancer-risk-60-percent"
categories:
  - "Cancer"
  - "Health & Medicine"
  - "Medical"
tags:
  - "bacteria"
  - "cancer"
  - "gut health"
  - "resistant starch"
---

# Study Suggests That Pill Can Cut Hereditary Cancer Risk by 60 Percent

![A new study shows that resistant starch has an astonishing ability to help prevent a range of hereditary cancers, cutting risk by 60 percent.](<https://futurism.com/wp-content/uploads/2022/07/study-pill-hereditary-cancer-risk-60-percent.jpg>)
*Cancer cells, illustration. \<em\>Image: Getty Images\</em\>*

A years-long trial appears to have shown that resistant starch — a digestion-resistant molecule found in a range of everyday foods including slightly underripe bananas, oats, peas and beans, rice, pasta and more — has an astonishing ability to help prevent a range of hereditary cancers.

Published [in the journal *Cancer Prevention Research*](<https://aacrjournals.org/cancerpreventionresearch/article/doi/10.1158/1940-6207.CAPR-22-0044/707189/Cancer-Prevention-with-Resistant-Starch-in-Lynch>), the double-blind longitudinal study followed nearly 1,000 patients with Lynch Syndrome, an inherited genetic condition that [increases the individual risk](<https://www.mayoclinic.org/diseases-conditions/lynch-syndrome/symptoms-causes/syc-20374714>) of several cancers, for almost 20 years.

According to a [press release](<https://scitechdaily.com/scientific-trial-proves-diet-supplement-can-prevent-hereditary-cancer/>), the researchers at the universities of Newcastle and Leeds placed participants in two groups back in 1999. There was a short treatment period thereafter, which lasted until 2005.

During the treatment period, each individual received a pill. One group took a placebo, while the other took a daily dose of resistant starch.

There was no notable difference in the individuals' health at the end of that short treatment period. But the study was designed for follow-up, and in extremely intriguing results, those who took the daily starch pill — which contained the approximate amount of the digestion-defying molecule that one would find in an average-sized underripe banana — were far more likely to be cancer-free nearly 20 years later.

"We found that resistant starch reduces a range of cancers by over 60 percent. The effect was most obvious in the upper part of the gut," John Mathers, professor of Human Nutrition at Newcastle University, said in the press release. "This is important as cancers of the upper GI tract are difficult to diagnose and often are not caught early on."

The researchers believe that the secret to resistant starch's success is in its ability to, well, resist.

Specifically, it resists acidic digestive bile. As a result, it actually settles and ferments in the large intestine. This feeds gut-supporting friendly bacteria, acting, as Mathers described in the press release, "like dietary fiber in your digestive system."

But how, exactly, might this defend against cancer?

According to the press release, the scientists believe that regular consumption of resistant starch — and thus, regularly keeping that good bacteria happy — might actually change the bacterial metabolism of the bile acids, ultimately keeping them from damaging DNA. (As the scientists concede in the press release, this theory needs more research.)

It's also worth noting that while the starchy supplement seemed to strongly support the upper GI tract and multiple other areas of the body, it wasn't shown to defend against bowel cancers.

But all in all, the results are promising. Perhaps a daily unripe banana — no offense, apples — is actually the best way to keep the doctor away.

**More on major breakthroughs:** *[Doctors Gene-edit Patient's Liver to Make Less Cholesterol](<https://futurism.com/neoscope/doctors-gene-edit-less-cholesterol>)*

## Author
At Futurism, I've reported extensively on the rise of AI as a cultural and business force shaping the media industry, and more broadly how those dynamics are changing how we all consume and share information and relate to one another. I'm also fascinated by public health policy and ethics, the role of emerging tech in politics and governance — and the powerful people and forces at those intersections — climate change, and the environment. My investigation on Sports Illustrated's use of AI-generated authors with fictional biographies won a 2024 Mirror Award for "Best Story on Media Coverage of Artificial Intelligence in Journalism and the Media" from Syracuse University's SI Newhouse School, I contributed to Niemen Lab's 2025 Predictions for Journalism series, and I've discussed my work for Futurism during appearances on NPR, CNN, the BBC, the CBC, and more. I grew up in rural Pennsylvania and attended the University of Massachusetts Amherst, where I played Division I field hockey for the Minutewomen as a midfielder. Since then, I've lived in New Orleans, Louisiana and Manhattan, New York. I spend my free time running, reading, perusing archival fashion, and searching for the world’s best negroni. I also have a debonair tuxedo cat, Westley, who's named after "The Princess Bride."

### Author social links  
[Bluesky](<https://bsky.app/profile/mharrisondupre.bsky.social>)