--- title: "Microplastics Getting Stuck in Brain Vessels Like Clots, Scientists Find, Causing “Neurological Abnormalities” in Mice" description: "Scientists tracked tiny pieces of microplastics as they moved through the brain blood vessels of mice. Some of them became stuck." date: "2025-02-11" modified: "2025-02-11" authors: - name: "Victor Tangermann" job_title: "Senior Editor" link: "https://futurism.com/authors/victor" url: "https://futurism.com/neoscope/microplastics-brain-vessels-clots-mice-scientists" categories: - "Developments" - "Health & Medicine" tags: - "blood-brain barrier" - "brain" - "mice" - "microplastics" --- # Microplastics Getting Stuck in Brain Vessels Like Clots, Scientists Find, Causing “Neurological Abnormalities” in Mice ![Scientists tracked tiny pieces of microplastics as they moved through the brain blood vessels of mice. Some of them became stuck.]() *\Image: Getty / Futurism\* For the first time, scientists have used real-time imaging to track tiny pieces of microplastics as they moved through the brain blood vessels of mice. As detailed in a recent [paper]() published in the journal *Science Advances*, first [spotted by *The Guardian*](), the project made an alarming discovery: some of the pieces of plastic were becoming stuck, causing more chunks to accumulate behind them in what [one of the researchers likened]() to a "car crash." In experiments, the international team of scientists found that mice that were exposed to microplastic experienced decreased motor function, hinting at the possibility that accumulating plastic may be having negative effects on the brain, including "neurological abnormalities." "This revelation offers a lens through which to comprehend the toxicological implications of microplastics that invade the bloodstream," the paper reads. It's an alarming — albeit preliminary — warning sign that microplastics, which have pervaded practically every part of our environment and our bodies, could be detrimental to our neurological health. Scientists have found tiny pieces of plastic chemicals in human [arteries](), [hearts](), [penises](), [semen](), and [lungs](). Microplastics have previously been [linked to reproductive health issues]() and [cancer risk](), among other issues. Now, given the latest study, the situation isn't looking great — especially as [concentrations of microplastics inside human bodies continues to rise](). The paper's authors gave mice water that was laced with fluorescent-coated polystyrene, allowing them to use an imaging technique called "two-photon microscopy" to track how they moved into the mice's brains. When encountering tight bends within the organs' cortex vessels, the tiny pieces of polystyrene appear to have gotten absorbed by immune cells, creating unusually-shaped cells that then become stuck. Some of these blockages became unstuck by themselves over time. However, the finding that stuck pieces of microplastics can get lodged in the first place and reduce blood flow is concerning. "Environment microplastics might be another important risk factor for cardiovascular disease and received scant attention so far," the researchers wrote. "Our findings provide a mechanistic explanation for tissue damage induced by microplastics, particularly regarding their effects on vascular obstruction." "This obstruction is likely to have detrimental consequences for cardiovascular health and may result in more severe adverse effects, especially in patients with underlying conditions similar to myocardial infarction," they concluded. But as the authors note, it's important to point out that we still don't know if the same blockages would take place in the human brain as well, as our vessels tend to be much larger. "Moreover, humans are exposed to a variety of \[microplastic\] sizes, and the combinatorial effects of different \[microplastic\] sizes on the likelihood of inducing infarctions remain to be estimated," they wrote in their paper. "The use of larger mammals or animal models that more closely resemble the human circulatory system, such as nonhuman primates, is thus crucial for studying this process." **More on microplastics:** *[The Weight of All the Plastic in Your Brain May Make You Queasy]()* ## Author I've been at Futurism since 2017, where my role has evolved to encompass design, writing, and increasingly editing. I've always been fascinated by space exploration and advanced transportation, which I've leaned into by interviewing luminaries in those fields while closely following the dimensions of policy and regulation that allow next-generation projects to succeed -- or, sometimes, to fail. I'm also keenly interested in the effects of generative AI on society, policies, and democratic institutions, as well as clean energy, physics and biology, and the vagaries of tech leadership. My work for Futurism has been cited by publications including Ars Technica, Gizmodo, PC Magazine, Jalopnik, Fox News, and the New York Post. I spent my childhood living in locations including Manila, the Philippines, and Geneva, Switzerland, attended McGill University, and now live in Toronto, Canada. Before Futurism I worked at AskMen and a small photography studio. In my free time, I'm an avid gardener, foodie, and craft beer lover, as well as a maker of artisanal hot pepper sauces. I have a magnificent dog named Freida. ### Author social links [Bluesky]()