• To achieve this objective, the three-phased program will focus on: 1) Development of a viral-evolution platform for generating datasets used to build and validate algorithms predictive of viral evolution.
  • 2) Refinement of the platform to include mechanisms capable of controlling multiple selective pressures and accompanying predictive evolutionary models and algorithms.
  • 3) Testing and validation of the system and algorithms using multiple selective pressures on at least three closely related virus strains in an experimental setting. Phase III will to attempt to replicate in a laboratory the viral mutations or evolutions that are documented to have occurred naturally.

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