• In a paper in Proceedings of the National Academy of Sciences, the engineers describe how they used a combination of natural and synthetic DNA to build complex machines that can perform repetitive tasks.
  • There are two keys to their unique approach for designing and controlling the machines’ motion: make certain parts of the structure flexible using single-stranded DNA and stiffer using double-stranded DNA, and “tune” the DNA structures so that the machines’ movements are reversible and repeatable.
  • Ultimately, the technology could create complex nanorobots to deliver medicine inside the body or perform nanoscale biological measurements, among many other applications.

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